Typology
Ph.D Course
Access methods
Restricted access
Duration
3 years
Location
Varese
Language
Italian
Structure
DIPARTIMENTO DI MEDICINA E CHIRURGIA

Course description

Biomedical research is among the main keys to progress and well being in modern societies, and the profession of biomedical researcher is among the most intellectually exciting.
Nonetheless, in the last decades pursuing a career as researcher in biomedicine has become more and more difficult, mainly due to increased competition and decreased funding. Pressure of severe competition for funds and to obtain and secure a staff position in academic institutions are among the major factors leading researchers to breach their professional integrity by adopting questionable research practices and ultimately committing scientific misconduct.
The PhD program in Clinical and Experimental Medicine and Medical Humanities aims at addressing the unmet needs of young scientists by providing a comprehensive knowledge of the fundamental principles, methodologies and practices of preclinical and clinical research.
According to ENAI, "academic integrity" means "compliance with ethical and professional principles, standards and practices by individuals or institutions in education, research and scholarship" (1). Research integrity may be defined as active adherence to the ethical principles (honesty, trustworthiness, and high regard for the scientific record)  and professional standards essential for the responsible practice of research (2).
Scientific misconduct results in harm to individuals and society, e.g. due to the development of ineffective and/or unsafe drugs or other therapeutics or just wasting money and resources in misconducted research activities, direct damage to science itself, by creating false leads for other scientists to follow, and/or forcing others to waste time, effort and money to reproduce fraudulent results, degradation of relations among scientists, between senior researchers and students, and between researchers and agency programme managers, damage to science through the undermining of the public’s trust in science (3).
Lack of knowledge/preparation about the realities and stresses of a scientific career as well as lack of awareness of the rules and standards of proper scientific conduct are among the main factors leading young researchers to scientific misconduct and career failure (3).
As a whole, this PhD program is thus addressed to young researchers planning to pursue their career into science and research, who would like to benefit from a thorough knowledge of the principles and methodologies underlying high quality research.
This PhD program is also part of an integrated project aimed at training “Physician-scientists”, defined as those with MD degrees who devote a substantial part of their professional effort to biomedical research, ranging from basic science, through translational and patient-oriented research, to advance medical sciences from the bench to the bedside and maintain rigorously high academic standards in basic and clinical research.

Scientific areas: 05 – Biological Sciences, 06 - Medical Sciences, 14 - Political and Social Sciences
Thematic areas: BIO/08, BIO/14, MED/01, MED/02, MED/07, MED/09, MED/10, MED/11, MED/13, MED/15, MED/17, MED/25, MED/26, MED/35, MED/39, MED/41, MED/42, MED/43, SPS/01
Coordinator : Squizzato Alessandro
Academic Year: 2025/2026
Ph.D. Cycle: XLI cycle

What you need to know

All graduates with a master's degree and, in particular, graduates in medicine and surgery, dentistry, veterinary medicine, literature and philosophy, communication sciences and techniques, biological sciences, biotechnologies, pharmacy, psychology, chemistry and technology can access the doctorate. pharmaceutical, legal and economic sciences. The possession of an adequate cultural education and a personal path suitable to undertake the doctorate course will be the subject of specific and in-depth verification and evaluation during admission.

At the beginning of the first year the Teachers' Committee of the Course assigns to each PhD student a guiding professor within the College and possibly an external tutor, with whom the PhD student agrees on the three-year research program. The guide teacher and the eventual tutor are responsible for the orientation and supervision of the student's activities. The students enrolled in the course annually present a report on the results achieved, which is presented at an annual scientific meeting. The educational and training activities (compulsory and optional) associated with each year of the course are defined annually by the Academic Board.

Graduates of this program can hold positions in both public and private institutions (hospitals, research laboratories, private companies, therapeutic counseling centers, and family planning clinics). Many find positions in local hospitals and public/private institutions, also fulfilling the important educational objective of postgraduate higher education programs: providing the university's regional offices with highly qualified and specialized personnel, with the aim of increasing professionalism and competitiveness in these sectors. Main areas of employment: Clinical facilities with a particular focus on research (IRCCS, university hospitals), public and private research institutes operating in the biomedical field, local health authorities and hospitals in the sectors dedicated to healthcare monitoring and planning, ethics committees for clinical trials, preclinical animal research), pharmaceutical industries (clinical and basic and applied research), institutes and organizations conducting research in the social, marketing, and communications sectors, with a focus on health and the prevention of organic and mental health conditions, including emerging ones (e.g., gambling, maladjustment disorders, addictions), institutes and organizations operating in the social sector, such as counseling centers, recovery centers, and community centers in the mental health sector, and ethics consulting services.

Enrollment

All information will be availablle as soon as possible.

Class attendance

Students enrolled in the Course are also required to attend training activities consistent with the Course's objectives and their research program. Attendance at training activities organized as part of the Course is mandatory.

Studying

School of Neuroimmune Pharmacology Years 1, 2, and 3: Neuroimmunopharmacology lies at the intersection of pharmacology, immunology, and neuroscience, thus characterized by a high degree of inter- and transdisciplinarity and offering original therapeutic approaches based on knowledge of the complex relationships between the nervous and immune systems. The primary objective of this discipline is the identification of new pharmacotherapeutic targets and the repositioning of existing drugs for other indications through a characterization of their neuroimmunological effects. Neuroimmunopharmacology is a relatively young scientific discipline, but one experiencing rapid and vibrant growth. In 1993, the Society on Neuroimmune Pharmacology (SNIP - https://s-nip.org/) was founded, in 2006 the Journal of Neuroimmune Pharmacology (Springer-Nature, https://link.springer.com/journal/11481) began publication, and in 2008 the first edition of Neuroimmune Pharmacology (JNIP, Springer) was published, followed in 2016 by a second updated and expanded edition (https://amzn.to/2OmZniT). This discipline is not limited to the study of inflammatory and autoimmune diseases of the nervous system (for example, multiple sclerosis and peripheral neuropathies, classic areas of interest in neuroimmunology), but also encompasses neurodegenerative processes such as Parkinson's and Alzheimer's disease, stress-related disorders, cardiovascular diseases, and, in general, all conditions in which peripheral and central inflammatory processes involve and/or are influenced by the nervous system. The School is an integral part of the teaching and training activities of the Doctoral Program. Thanks also to the collaboration of its sponsoring scientific societies, the School is promoted internationally.

School on Methodology, Ethics and Integrity in Biomedical Research

I, II, and III years: This School was created within the PhD program in Clinical and Experimental Medicine and Medical Humanities, and incorporates the doctoral programs that have merged into it, namely the program in Clinical and Experimental Pharmacology and the program in Medicine and Human Sciences. Consistent with the program's stated objectives ("to provide the methodological skills to design and conduct experimental and clinical research from a global and systemic perspective that also leads to in-depth reflection on the ethical and deontological aspects related to basic and applied experimental research in clinical practice and in pharmacological and non-pharmacological therapy"), the faculty who created this highly innovative and interdisciplinary program now intend to develop an additional tool, integrated into the postgraduate curriculum, useful for pursuing the goal of promoting a culture of scientific integrity in biomedicine. The University of Insubria stands out nationally for its specific attention to these highly topical and globally relevant issues, which are still largely absent from the political and strategic debate of Italian scientific research. Our university has adopted a Code of Ethics that—like no other Italian university to our knowledge—deeply addresses issues such as conflict of interest and integrity in scientific research. In this regard, and for the purposes of this School project, the experience of the seminar series on the Code of Ethics, promoted and organized by the working group that drafted the Code (which included some of the proponents of this School), is extremely significant. The seminar series has enjoyed considerable success and attention, thanks in part to the publication of the full videos online.

Annual Science Day First, second, and third year: 

Biomedical research is among the crucial factors for the progress and well-being of modern societies, and the profession of biomedical research is among the most intellectually exciting. In recent decades, however, pursuing a research career in biomedicine has become increasingly difficult, primarily due to increased competition and declining funding. The pressure of intense competition for funding and securing stable employment in academic institutions are among the major factors driving researchers to compromise their professional integrity by adopting questionable research practices, even committing acts of scientific misconduct.

VIRT2UE, Training program for research integrity

Modules

  1. The European Code of Conduct for Research Integrity
  2. Introduction to research integrity - a module that introduces the basic principles of research integrity and asks you to apply the European Code of Conduct to your own context.
  3. Introduction of Virtue Ethics to Research Integrity - a module that introduces the relevance of virtue ethics to research integrity and asks you to reflect about research integrity issues.
  4. Virtue ethics applied under current research conditions - a module that addresses more systemic issues, like performative pressures in research, and relates these to virtue ethics and the individual experience of the researcher. 

The PhD Program in Clinical and Experimental Medicine and Medical Humanities aims to meet the training needs of young researchers by providing comprehensive and up-to-date knowledge of the fundamental principles, methodologies, and practices of preclinical and clinical experimental research in biomedicine.

The annual scientific day, now in its eighth year (https://tinyurl.com/y8vuyxag), is a consolidated event of great educational value for doctoral students who thus learn the fundamentals of communication and discussion in scientific conferences


 

Course committees and representatives

The PhD Faculty Board is composed of professors from the University of Insubria, as well as scholars from other Italian universities.

  1. ANGELI Fabio
  2. BELLINI Paolo
  3. CALLEGARI Camilla
  4. CAMPIOTTI Leonardo
  5. COSCIA Marta
  6. COSENTINO Marco
  7. DALLA GASPERINA Daniela
  8. DENTALI Francesco
  9. GORINI Ilaria
  10. GUASTI Luigina
  11. IETTO Giuseppe
  12. LICATA Marta
  13. MARESCA Andrea
  14. MARINO Franca
  15. MARTINELLI BONESCHI Filippo - Università degli Studi di Milano La Statale
  16. NOVAZZI Federica
  17. PICOZZI Mario
  18. PORTA Giovanni
  19. SEVERGNINI Paolo
  20. SPANEVELLO Antonio
  21. SQUIZZATO Alessandro
  22. STORACE Erasmo Silvio
  23. TANDA Maria Laura Piera
  24. TERMINE Cristiano
  25. VERONESI Giovanni
  26. VERSINO Maurizio
  27. ZERBINATI Nicola
  28. BASU Sujit - Scuola Universitaria Superiore Pisa Sant'Anna
  29. FABBRI Alice
  30. KAUL Marcus
  31. KOSMAN Jan-Pieter
  32. MEUCCI Olimpia
  33. PACHECO Rodrigo
  34. PEREIRA C. Frederico 
  35. PEREIRA RIBEIRO TEIXEIRA Laura Virginia
  36. ROMERO RAMOS Marina

The AiQUA Committee is responsible for overseeing the quality assurance of all teaching and research activities within the PhD Program. It liaises with the Faculty Board, the Doctoral School, and the Department Council.
The Committee is composed of the Coordinator, four members of the Faculty Board, and one PhD student representative.

Find out more:

The Advisory Committee plays a strategic role in ensuring the quality of the PhD program, guaranteeing that its structure, content, and training activities meet high academic standards and follow best practices. It also helps keep the program aligned with research trends, societal needs, and labor market demands, ensuring that PhD candidates develop skills that are valuable both in academic and professional contexts.

Find out more:

For information

Centro Interdipartimentale di Ricerca in Farmacologia Medica

Via Monte Generoso n. 71
21100 Varese VA
Tel. +39 0332 217401/397401
Fax: +39 0332 217409/397409
Email farmacologia.medica@uninsubria.it 
dottorato.dmc@uninsubria.it

For information

Centro Interdipartimentale di Ricerca in Farmacologia Medica

Via Monte Generoso n. 71
21100 Varese VA
Tel. +39 0332 217401/397401
Fax: +39 0332 217409/397409
Email farmacologia.medica@uninsubria.it 
dottorato.dmc@uninsubria.it