Degree course: 
Corso di First cycle degree in Physiotherapy
Academic year when starting the degree: 
Academic year in which the course will be held: 
Course type: 
Basic compulsory subjects
First Semester
Standard lectures hours: 
Detail of lecture’s hours: 
Lesson (14 hours)


Voto Finale

To know the molecular bases of biological phenomena, mostly those important in physiology, diseases, and clinical practice, at the level of cells, tissues and total body. To approach the own language and method of experimental life sciences.

1) Solutions: water properties, solvation and electrolytes, hydrogen bond, concentration of the solutions.
2) Acid base balance: fundamentals (strength of the acids and the bases pH, pK), buffering, biological buffers, Handerson-Hasselbalch equation
3) Organic compounds. Functional groups: alcohol, aldehydes, ketones, carboxyl acids, amines. Nomenclature and main characteristics. Main types of isomers. Aromatic compounds.
4) Aminoacids and protein structure; Collagen.
5) Myoglobin and hemoglobin, cooperativity and allosteric interactions.
6) Reaction kinetics: enzymes and enzymatic kinetics
7) Bioenergetics: principles of the thermodynamics, free energy and spontaneous reactions, high energy bonds.
8) Bioenergetics: redox potentials, redox pairs of particular biological importance, oxidative phosphorylation.
9) Tricarboxylic acid cycle
10) Carbohydrates: mono- and polysaccharides. Glycogen metabolism
11) Glycolysis and its regulation
12) Gluconeogenesis and hexose monophosphate shunt
13) Lipids. Fatty acids, triglycerides and phospholipids.
14) Biosynthesis and beta-oxidation of fatty acids
15) Cholesterol and steroid hormones
16) General metabolism of aminoacids and nitrogen-containing compounds; Transamination and oxidative deamination
17) Nucleic acids; nitrogenous bases and nucleotides
18) Metabolic interactions: feed-starve cycle, biochemical aspects of diabetes.

All didactic material presented in the classes as well the one necessary for the preparation of the examination (slides, pantries, exercises) is available in the e-learning platform.
Textbook suggested(in Italian):
Champe PC, Harvey RA, Ferrier DR – Le basi della biochimica – Zanichelli.
M. Samaja, R. Paroni - Chimica e Biochimica per le lauree triennali dell’area biomedica – Piccin editore
Multiple choice questionaire plus oral interviewMultiple choice questionaire plus oral interview