Degree course: 
Corso di Second cycle degree in BIOMEDICAL SCIENCES
Academic year when starting the degree: 
Academic year in which the course will be held: 
Course type: 
Supplementary compulsory subjects
Second semester
Standard lectures hours: 
Detail of lecture’s hours: 
Lesson (48 hours)

Good knowledge of Physiology and Neurophysiology in particular

Final Examination: 

The exam consists closed-answer quiz on the basic topics of the course and a discussion and critical evaluation of an article related to one of the pathologies treated during the course. The ability to propose future advancements or alternative approaches to improve the knowledge of the proposed subject will be evaluated. The student has to demonstrate that he/she has learned the cellular and molecular aspect of the pathophysiological problem, that he/she has critically read the scientific literature relating to the field of the assigned article and that he/she is able to apply the knowledge in the future development of a new method of investigation, of a new drug or a new diagnostic approach, identifying the main steps that a research project requires.
A minimum requirement for passing the exam is to be able to conduct a scientific discussion with appropriate terms relating to the teaching subjects by presenting one's work with the aid of multimedia presentations. The final grade is expressed out of thirty based on the evaluation of the Examination Committee with reference to the aspects set out above but also taking into account the personal contribution along with the classes discussion during the teaching hours.

Voto Finale

At the end of the course, the student will be capable of:
- Understanding how the molecular and cellular processes in neurons and glia and the organization of neural circuits give rise to sensory information processing, motor control, sleep, memory, learning, emotions, language, thought and motivated behaviour
- describing the specific features of Central Nervous System physiology and pathology, of the neuron-glia interaction, of the processes of neurodegeneration and of possible strategies of neuroprotection
-Hypothesize how genetic and environmental factors and psychological experience may interact in generating neurological and psychic disturbances.
- Explaining the modalities of onset and the main features of the most important CNS pathologies (Parkinson's, Huntington's, Alzheimer's diseases, epilepsy and migraine, ALS, Schizophrenia, Depression, Bipolar Spectrum Disorders, Autistic Spectrum Disorders, ADHD)
-Defining the main Neuroscience research approaches for studying CNS Pathologies and developing their therapies.

Neuroscience approaches and Methods for studying the CNS and its Pathologies
Neurons, neurotransmitters, synapses and glia
Overview of the organization of the CNS
The organization of the central nervous system
Sensory system and central processing of sensory information
Integration of the information
Synaptic plasticity and Memory
Attention, learning
Motor Control
Anxiety, Depression, Bipolar Spectrum Disorders, Post Traumatic Stress Disorder
Amyotrophic Lateral Sclerosis (ALS)
Parkinson’s Disease (PD)
Alzheimer’s Disease (AD)
Migraine and Epilepsy
Autistic Spectrum Disorders, Attention Deficit Hyperactive Disorder

Principles of neural science 5th Edition
di Eric R. Kandel, John D. Koester, e al.
McGraw-Hill Education;
ISBN-10 ‏ : ‎ 9780071390118
ISBN-13 ‏ : ‎ 978-0071390118

Neuroscience. Purves, D., et al. (2018)6th Edition, Sinauer Associates, New York.
ISBN-10 ‏ : ‎ 160535841X
ISBN-13 ‏ : ‎ 978-1605358413


Teaching activity consists of classical lectures supported by multimedia presentations, expert seminars, but also activity of flipped classes where recent physiopathological literature, video, movies are scientifically discussed.
The flipped class activity will be part of the final evaluation