MICROBIOLOGIA E VIROLOGIA

Degree course: 
Corso di First cycle degree in Biomedical Laboratory techniques
Academyc year when starting the degree: 
2018/2019
Year: 
2
Academyc year when helding the course: 
2019/2020
Course type: 
Compulsory subjects, characteristic of the class
Credits: 
2
Period: 
Second semester
Standard lectures hours: 
14
Detail of lecture’s hours: 
Lesson (14 hours)
Requirements: 

Basic biology knowledge

Written test; three open questions about as much program topics

Assessment: 
Voto Finale

Acquisition of basic knowledge of viruses
Acquisition of principles underlying the human-virus interaction
Acquisition of basic knowledge of diagnostic virology

Structure of viruses.
Host, organ and tissue tropism
Cellular infection with animal viruses
Principles of diagnostic virology

Structure of animal viruses.
Size and morphology of viral particles; organization of RNA and DNA viral genomes
Structure of capsid and envelope; virion enzymes; other components.
Host, organ and tissue tropism
Principles of virus classification
Virus replication.
Cellular infection with animal viruses: receptor binding, penetration, uncoating,
expression of the viral genome.
DNA and RNA virus replication.
Assembly, maturation and release of viral particles
Cytopathic effect: morphological aspects and molecular mechanisms.
Mutations, genetic recombination and gene reassortment as cause of viral variability.
Pathogenesis of viral infections.
Sensitivity of cells to infection.
Acute, latent and persistent viral infections
Principles of diagnostic virology: direct and indirec tests

Microbiologia medica
Patrick R. Murray, Michael A. Pfaller, Ken S. Rosenthal
Edra editore

Convenzionale

Frontal lessons; slides available to the student on e learing platform. On the same platform, in-depth tools are provided to the student (scientific articles and material from dedicated websites)

Availability to meet students by appointment
e mail: andreina.baj@uninsubria.it