Degree course: 
Corso di First cycle degree in Dental Hygiene
Academic year when starting the degree: 
Academic year in which the course will be held: 
Course type: 
Basic compulsory subjects
First Semester
Standard lectures hours: 
Detail of lecture’s hours: 
Lesson (24 hours)

A thorough comprehension of the course entails basic knowledge of general chemistry, biochemistry, human physiology and general pathology (imparted during the first year).

Voto Finale

The course aims to provide the student with information on the general principles underlying the interaction between human organism and medicines and their mechanism of action. In particular, knowledge will be provided on the setting of correct dosing and drug-related risk assessment related to various factors (administration, adverse effects, drug intolerance, and pharmacological interactions). The course aims to provide pharmacological and toxicological bases for the management and use of medicines in hospital and in dentistry. The course aims to provide the students with information concerning the pharmacological and toxicological properties of the most important therapeutic classes of drugs. The main pharmacokinetic properties, the mechanism/s of action, therapeutic use, interaction/s with other drugs and adverse effects will be described for each group of drugs considered in the program.

The course encompasses the following topics of Pharmacology:

- Elements of Pharmacokinetics: main routes of drug administration, and the pharmacokinetic processes of absorption, distribution, metabolism and elimination of drugs in healthy subjects, in patients, during pregnancy and in puerperium. Quantitative pharmacokinetic topics will also be used to set a correct dose, such as distribution volume, clearance, half-life, maintenance dose, and loading dose. The concept of bioavailability and the equivalent drug will be addressed.

-Elements of Pharmacodynamics: main mechanisms underlying drug action, theoretical basis for the interpretation of drug action by imparting the concepts of agonist, antagonist, partial agonist. Dosage-response curves that allow to interpret efficacy and pharmacological potency. Drug-toxicology topics will be addressed to interpret toxic drug effects, drug interactions, abuse, tolerance, addiction.
The course will encompass topics of Clinical Pharmacology. In particular the main pharmacokinetics and pharmacodynamics characteristics, adverse effect and drug-interaction of anti-inflammatory non steroideal drugs, corticosteroids; opioid analgesics, local and general anaesthetics, drugs used in the treatment of anxiety; drugs acting on coagulation disorders; antibiotic chemotherapy; drugs affecting the gastrointestinal function.

General and Clinical Pharmacology. Katzung B.G. McGraw Hill Ed LANGE. XIV Edition

Pharmacology. Rang, Dale, Ritter, Flower, Henderson. Elsevier