ANESTHESIOLOGY AND PHARMACOLOGY
- Assessment methods
- Learning objectives
- Teaching methods
A thorough comprehension of the course entails basic knowledge of general chemistry and biochemistry (Course of Biomedical Sciences, imparted during the first year), Physiology and General Pathology (Course of Pathophysiological basis of life, imparted during the first year). There are no constraining pre-requisites for this course.
Knowledge verification is based on an oral examination concerning the subjects and skills discussed during the frontal lessons. The objective is to verify whether the student has reached the previously described formative objectives and will be pursued by evaluating the degree of knowledge and deepening of the different subjects. In particular, the degree of knowledge and understanding will weigh the 40% of the final vote, the ability to apply the knowledge and skills acquired during the lessons will weigh the 25% of the final vote, the autonomy of judgement will weigh the 25% and the communicative skills will weigh the 10%. Evaluation will be expressed in 30/30, and a minimal score of 18/30 will be necessary to pass. The score obtained in the course of Pharmacology will be added to that obtained in Anaesthesiology, and the final vote will consists of the median value. In case that the evaluation will result negative (insufficient, below 18/30) even in just one of the two disciplines, the student fails the exam and will have to repeat the whole exam on the next call.
The course aims to provide the student with information on the general principles underlying the interaction between human organism and medicines and their mechanism of action. In particular, knowledge will be provided on the setting of correct dosing and drug-related risk assessment related to various factors (administration, adverse effects, drug intolerance, and pharmacological interactions). The course aims to provide pharmacological and toxicological bases for the management and use of medicines in hospital and in dentistry. The course aims to provide the students with information concerning the pharmacological and toxicological properties of the most important therapeutic classes of drugs. The main pharmacokinetic properties, the mechanism/s of action, therapeutic use, interaction/s with other drugs and adverse effects will be described for each group of drugs considered in the program
The course encompasses the following topics of Pharmacology:
- Elements of Pharmacokinetics: main routes of drug administration, and the pharmacokinetic processes of absorption, distribution, metabolism and elimination of drugs in healthy subjects, in patients, during pregnancy and in puerperium. Quantitative pharmacokinetic topics will also be used to set a correct dose, such as distribution volume, clearance, half life, maintenance dose, and loading dose. The concept of bioavailability and the equivalent drug will be addressed.
-Elements of Pharmacodynamics: main mechanisms underlying drug action, theoretical basis for the interpretation of drug action by imparting the concepts of agonist, antagonist, partial agonist. Dosage-response curves that allow to interpret efficacy and pharmacological potency. Drug-toxicology topics will be addressed to interpret toxic drug effects, drug interactions, abuse, tolerance, addiction.
The course will encompass topics of Clinical Pharmacology. In particular the the main pharmacokinetics and pharmacodynamics characteristics, adverse effect and drug-interaction of
Anti-inflammatory drugs: non steroideal anti-inflammatory drugs, corticosteroids
-Opioid analgesics, local and general anaesthetics, drugs used in the treatment of anxiety;
-Drugs acting on the blood: anticoagulants, antiplatelet drugs;
Drugs affecting the gastrointestinal function., will be discussed
Farmacologia generale e clinica. Katzung B.G. Piccin Ed IX edizione italiana sulla XII edizione di lingua inglese
Farmacologia. Rang, Dale, Ritter, Flower, Henderson. Elsevier Ed. VII edizione italiana
The course consists of 24 hours of frontal lectures involving slides projection (prevalently written in Italian, but in cases of recent publication material, also in English). During classroom discussions, students are encouraged to interact with the lecturer with questions and curiosities. During lectures, lecturers will also present everyday cases and facts that can make it clear the application/importance of the subjects treated during the lessons. Students are required to attend the lessons as set out in the teaching regulations of the course and sign the attendance sheet to be able to take the exam. Lesson presentations will be available on accessible computerized platforms provided by the University (eg e-learning) to each student.
Presentations may provide links to web pages for further information. Student reception is obtainable on appointment via email.