CHEMISTRY AND PROPEDEUTIC BIOCHEMISTRY

Degree course: 
Corso di Long single cycle degree (6 years) in MEDICINE AND SURGERY
Academic year when starting the degree: 
2016/2017
Year: 
1
Academic year in which the course will be held: 
2016/2017
Course type: 
Basic compulsory subjects
Credits: 
5
Period: 
First Semester
Standard lectures hours: 
50
Detail of lecture’s hours: 
Lesson (50 hours)
Requirements: 

Prerequisites
The course prerequisites are the basic knowledge of the fundamentals of general chemistry.

Final Examination: 
Orale
Assessment: 
Voto Finale

Objectives and expected results
The course objectives are related to the presentation and discussion of fundamental aspects of chemistry applied to medicine including introductory notions of medical biochemistry.

Content and course program
Atom structure: nucleus, nature and dimension, coulombian barrier, mass defect, chemical nuclear bond energy, atomic mass number, nucleons energy, radioactivity, (alpha, gamma) energy and material interaction, radioactivity measurements, radio nuclides in medicine, nuclear reactions. Electrons. Bohr atomic model, Heisenberg principle, electrons as ondulatory waves, steady state waves of the electrons, atomic orbital, quanta numbers, shape of the orbital, electronic configuration, periodicity of electrons configuration, periodicity of the elements properties.
Ionic and covalent bonds, Lewis rules, chemical bonds formation, molecular orbital theory, valent, energy and strength of the bond.
Gas volume and pressure, Rules of Boyle, Charles Gay Lussac, Avogadro, Dalton. Perfect gas rule, gas kinetic theory, gas diffusion and effusion, real gases rules. Viscosity, superficial tension, solid-liquid interactions, vapour tension, boiling point, phase diagram, Thermodynamic: enthalpy, entropy, free energy. Solutions, conjugate properties of solutions, volatile solutions, osmosis and osmotic pressure. Chemical equilibrium. Acids, Bases, Arrhenius, Broensted and Lewis definitions. Ionic water product. PH. Chemical Kinetics. Descriptions of the fundamental properties of H, Li, Na, K, Mg, Ca, B, C, N, P, O, S, F, Fe, Cu.
ORGANIC CHEMISTRY: Carbon geometry and hybridisation. Structural and functional isomers, conformational isomers, stereoisomerisms, Fundamental reactions of organic chemistry, substitution with radicals, with electrophiles and nucleophiles, addition of electrophiles and nucleophiles. Alcans, alchens and alchins, cycloalcans, Dienes, Aromatics and principal components of benzene derivatives, halogens, alcohols, polyalcohols, Tiols, phenol, aldheydes, ketones, carboxylic acids and their derivatives, ammines, amides,
Teaching activities
Frontal lessons

Textbook and teaching material
Masterton Chemistry
Clayden Greeves Organic chemistry
Exam
quiz with multiple Answers and oral exam