Degree course: 
Corso di Second cycle degree in CHEMISTRY
Academic year when starting the degree: 
Academic year in which the course will be held: 
First Semester
Standard lectures hours: 

Deep knowledge of basic Organic Chemistry, particularly with respect to aliphatic and aromatic reactivity

The final exam consists of a written test and a final oral presentation on a special topic on choice by the student

Voto Finale

The course has the aim to provide students with advanced knowledge of Organic Synthesis including the most innovative methods for the formation of carbon-carbon and carbon-heteroatom bonds

Conformational analysis of ring systems. Ring synthesis. Ring expansion and contraction processes.
Stereoselective methodologies in carbon-carbon bond formation: stereoselective formation of kinetic enalates. Alkylation of enolates. Aldol condensation from preformed enolates.

Olefination reactions.
Carbon-carbon and carbon-heteroatom bond formation mediated by transition metal complexes. Metathesis reactions
Total synthesis of natural products and bioactive compounds
Novel methodologies and novel reagents in Organic Synthesis

Lectures (64 hrs)

During the lectures slides and didactic support will be delivered and here there are only few examples of consultation textbooks.

F.A.Carey , R.J.Sundberg Advanced Organic Chemistry Part B (Reactions and Synthesis) Springer Science 2007, 5th Edition

S. Warren, P. Wyatt - Organic Synthesis: the Disconnection Approach
S. Warren, P. Wyatt - Organic Synthesis: Strategy and Control
E. J. Corey, Xue-Min Cheng - The Logic of Chemical Synthesis
K.C. Nicolaou, E.J. Sorensen - Classics in Total Synthesis
K.C. Nicolaou, S.A. Snyder - Classics in Total Synthesis II
K.C. Nicolaou, J.S. Chen - Classics in Total Synthesis III
T. Hudlicky, J.W. Reed - The Way of Synthesis
K.C. Nicolaou, T. Montagnon - Molecules that changed the world
E.J. Corey, L. Kurti, B. Czako - Molecules and Medicine
M.B. Smith - Organic Synthesis

The course will be delivered through seminars and lectures by the teachers