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Contact data |
Assistant Professor |
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Biography |
Dr. Imperatori qualified
as Medical Doctor at the University of Pavia School of Medicine in
1994. After spending part of his professional training at the European
Institute of Oncology, Milano (September 1995-May 1996), in the year
2000 he completed his graduate work in General Surgery at the University
of Insubria, Varese. Dr. Imperatori's specific clinical interests include surgical infections, detection and treatment of early lung cancer, general thoracic surgery, pleural mesothelioma and minimally invasive surgery such as video-assisted thoracic surgery (VATS). Dr. Imperatori has been actively involved in the development of several research projects. These include: treatment with high-dose immunoglobulins in severely septic patients; early postoperative internal nutrition in gastrointestinal cancer patients; a lung cancer screening program in the Province of Varese, Italy, named Progetto PRE.DI.CA.; translational research for the identification of target therapy for lung cancer and pleural mesothelioma. He cumulatively spent one year at the University Hospitals of Stockton-on-Tees and Hartlepool, Great Britain, in an Honorary Research Post, during 2000-2001 carrying out comparative research on lung cancer epidemiology and treatment in Teesside (UK) and the Province of Varese (Italy). He is currently a research fellow in General Surgery at the School of Medicine at the University of Insubria in Varese, where he teaches academic courses in three graduate schools (General Surgery, Thoracic Surgery and Respiratory Diseases), and three specific Courses for physiotherapists, radiologic technicians, and clinical laboratorists. |
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Qualifications and awards |
General certificate of
education obtained at Liceo Classico "S.M. Legnani" in Saronno,
Italy, 1987 Medical Doctor qualification degree obtained at the University of Pavia, 1994. Thesis: "Therapy of severe surgical infections with high-dose immunoglobulins.” Medical licensure: University of Pavia, 1995 Specialized in General Surgery, 2000 |
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Research interests |
Surgical Infections: identification of the high risk surgical patient; antibiotic prophylaxis and treatment; high-dose immunoglobulins in severely septic patients. Surgical Nutrition: nutrition and infection in surgical patients; Immediate postoperative enteral nutrition. Surgical Oncology: high risk cancer patients; detection and treatment of early lung cancer; lung cancer screening; malignant pleural mesothelioma. Mininvasive surgery: advances in video-assisted thoracoscopic surgery; localization and treatment of small lung nodules. Translational Research: applied to lung cancer and to pleural mesothelioma. |
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Teaching experience and appointments |
Research Fellow, Assistant
Professor in Surgery, 2001-present Member of the Scientific Committee of the Center of Thoracic Surgery, University of Insubria (2003-2005 and 2005-2008) Member of the Postgraduate Course of Doctorate in Surgery and Biotechnologies, University of Insubria (2003-present) Member of the Council of the Postgraduate School in General Surgery Member of the Council of the Postgraduate School in Thoracic Surgery Member of the Council of the Postgraduate School in Respiratory Diseases Official Course of General Surgery (for radiologic technician; for clinical laboratorist) Official Course of Thoracic Surgery (for physiotherapist) |
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Representative publications |
1. Gennari R, Dominioni
L, Imperatori A, Bianchi V, Maroni P, Dionigi R. Alterations in lymphocyte
subsets as prognosticators of postoperative infections. Eur J Surg,
161: 493-499, 1994. 5. Dominioni L, Bianchi V, Imperatori A, Minoia G, Dionigi R. High-dose intra-venous IgG for treatment of severe surgical infections. Dig Surg 13, 430-434, 1996. 6. Aftab F, Stoldt S, Testori A, Imperatori A, Chinol M, Paganelli G, Geraghty J. Radioimmunoguided surgery and colorectal cancer. Eur J Surg Oncol, 22:381-388, 1996. 7. Testori A, Grana C, Zoboli S, De Cicco T, Fiorenza M, Prisco G, Chinol M, Imperatori A, Trevisan C, Ukpabi E, Geraghty J, Paganelli G. Immunolymphoscintigraphy and sentinel node biopsy in high risk stage I melanoma patients. Eur J Surg Oncol, 22:417-418, 1996. 8. Ochetti A, Alberio MG, Frattini V, Imperatori A, Giovanella L, Dominioni L, Dionigi R. Early postoperative variations of markers CYFRA 21-1 and CEA in stage I-II non-small cell lung cancer (NSCLC) undergoing radical resection. J Jpn Surg Soc, 99:401, 1998. 9. Imperatori A, Rovera F, Dominioni L, Berizzi F, Frattini V, Interdonato PF, Benevento A, Dionigi R. Infections after oesophagectomy: the role of blood transfusion and other risk factors. Br J Surg, 86:837, 1999. 10. Dominioni L, Imperatori A, Rovera F, Dionigi G. Minimizing risk in gastrointestinal surgery. Shock 2000;13:176. 11. Dominioni L, Strauss GM, Imperatori A, Rovera F, Dionigi G. Screening for lung cancer. Chest Surgery Clinics of North America 2000;10:729-36. 12. Dominioni L, Imperatori A, Rovera F, Ochetti A, Torrigiotti G, Paolucci M. Stage I non-small cell lung cancer (NSCLC): analysis of survival and implication for screening. Cancer 2000;89(S):2334-44. 13. Dominioni L, Imperatori A, Rovera F, Ochetti A, Paolucci M, Dionigi G. Lung cancer screening in cigarette smokers in the province of Varese, Italy. Cancer 2000;89(S):2345-8. 14. Imperatori A, Leitch DN, Lepore G, Rovera F, Dionigi G, Harrison RN. Lung cancer in Northern Italy and Northern England: a comparison of two district general hospitals. Am J Resp Crit Care Med, 2001:163:A73. 15. Dionigi R, Rovera F, Dionigi G, Imperatori A, Ferrari A, Dionigi P, Dominioni L. Risk factors in surgery. J Chemother 2001;13(1):6-11. 16. Imperatori A, Rovera F, Dionigi G, Carcano G, Dominioni L. Finger palpation for identification of small pulmonary nodules undergoing video-assisted thoracoscopic (VATS) resection. Cardiovascular Engineering 2002;7(1):30. 17. Dominioni L, Imperatori A, Rovera F, Dionigi G, Vassallo F. The role of videothoracoscopy in the early diagnosis of lung cancer. Osp Ital Chir 2002;8:248-53. 18. Dominioni L, Imperatori A. Trachea (IT). In: R. Dionigi: Chirurgia, Masson III Ediz., 2002, pp. 892-8. 19. Dominioni L, Dionigi G, Imperatori A, Ochetti A. Lung (IT). In: R. Dionigi: Chirurgia, Masson III Ediz., 2002, pp. 899-929. 20. Carcano G, Imperatori A, Uccella L, Pelosi L, Dominioni L. Trasversal thoraco-mediastinal impalament: case report of a survival patient (IT). Ann Ital Chir 2002, 73(1):271-4. 21. Rovera F, Imperatori A, Militello P, Morri A, Antonini C, Dionigi G, Dominioni L. Infections in346 consecutive video-assisted thoracoscopic procedures. Surgical Infections 2003, 4(1):45-51. 22. Rovera F, Imperatori A, Antonini C, Cardani M, Dominioni L. Pneumonia after lung resection: analysis of risk factors and of surgical access in 640 cases. Surgical Infections 2003;4. 23. Imperatori A, Paddeu A, Rovera F, Bascialla L, Dominioni L. Epidemiology of pleural mesothelioma in the Province of Como in the years 1996-2000. Proceedings of the International Conference Pleural Mesothelioma, Como 7-8 November 2003, pp 41-48. 24. Dominioni L, Imperatori A, Rovera F, Paolucci M, Paddeu A. The fairy-tale of overdiagnosis of lung cancer. Proceedings of the International Conference Lung Cancer Screening and Early Diagnosis, Como 8 November 2003, pp 20-34. 25. Dominioni L., Rovera F., Pericelli A., Imperatori A. The rationale of early enteral nutrition. Acta Bio Medica, 2003,74(S2):41-4. 26. Rovera F, Militello P, Antonini C, Imperatori A, Dominioni L. Postoperative Candida pneumonia after 500 lung resections (IT). Minerva Chirurgica, 2003, 59(1):45-51. 27. Cesario A, Trombino S, Galetta D, Margaritora S, Murolo C, Dominioni L, Imperatori A, Festi L, Granone P, Russo P. Non-small cell lung cancer: from cytotoxic systemic chemotherapy to molecularly targeted therapy. Curr Med Chem Anti-Cancer Agents, 2004, 4:231-245. 28. Cesario A, Russo P, Viaggi S, Trombino S, Imperatori A, Margaritora S, Dominioni L, Festi L, Porziella V, Granone P. Malignant pleural mesothelioma: time for translational research. The Lancet Oncology 2004;5: 591. 29. Russo PA, Catassi A, Cesario A, Imperatori A, Rotolo N, Fini M, Granone P, Dominioni L. Molecular Mechanisms of Hexavalent Chromium-induced Apoptosis in Human Bronchoalveolar Cells. Am J Respir Cell Mol Biol. 2005 Sep 15; [Epub ahead of print] 30. Imperatori A, Harrison RN, Leitch DN, Rovera F, Lepore G, Dionigi G, Sutton P, Dominioni L. Lung cancer in Teesside (UK) and in Varese (Italy): a comparison of management and survival. Thorax 2005, accepted, in press online first. |
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Clinical interests |
Surgical infections
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