Department of Surgical Sciences
General and Thoracic Surgery, Ospedale di Circolo, Viale Borri,
57 – 21100 Varese (Italy)
|Lorenzo Dominioni was born
in Como, Italy, on Aug. 27, 1949. Graduated from the Faculty of Medicine
at the University of Pavia, Italy in 1974. Board of general surgery,
University of Pavia in 1980.
Academic career started as researcher in surgery at the University
of Pavia (from 1980 to 1993). Appointed associate professor of surgery
at the University of Pavia and at the University of Insubria in Varese,
from 1993 to 2000. Appointed professor of Surgery at the University
of Insubria in 2000.
Current position: Professor of Surgery, University of Insubria, Varese,
Italy. Director of the Unit of General and Thoracic Surgery of the
Department of Surgical Sciences of the University of Insubria, Varese.
Director of the Center for Thoracic Surgery, University of Insubria,
Ospedale di Circolo di Varese, Italy.
Surgical Practice: General surgery and thoracic surgery (over 6,000
cases operated. Over 600 cases operated by video-assisted-thoracoscopy
or by video-assisted-laparoscopy).
Publications: Author / co-author of more than 350 scientific papers
in the field of thoracic surgery and lung cancer, surgical infections,
artificial nutrition surgical oncology.
Membership in Professional Societies: American College of Surgeons,
International Association for Study of Lung Cancer (IASLC), Surgical
Infection Society - Europe (President 1998-99), International Society
for Diseases of the Esophagus, International Surgical Group. Member
of European Association for Cardiothoracic Surgery (EACTS).
|Graduated from the Faculty
of Medicine at the University of Pavia, Italy in 1974. Board of general
surgery, University of Pavia in 1980.
|Current research interests:
early diagnosis and screening for lung cancer; management and VATS
resection of small indeterminate lung nodules
identification of the high risk surgical patient;
antibiotic prophylaxis and treatment;
high-dose immunoglobulins in severely septic patients.
nutrition and infection in surgical patients;
Immediate postoperative enteral nutrition.
high risk cancer patients;
detection and treatment of early lung cancer;
lung cancer screening;
malignant pleural mesothelioma.
advances in video-assisted thoracoscopic surgery;
localization and treatment of small lung nodules.
applied to lung cancer and to pleural mesothelioma.
|Current position: Professor
of Surgery, University of Insubria, Varese, Italy.
Lecturer in thoracic surgery and in Surgical Semeiotics at the School
of Medicine of the University of Insubria in Varese since 1987.
Lecturer in Surgery at the Postgraduate Schools of Surgery and of
Director of the Unit of General and Thoracic Surgery of the Department
of Surgical Sciences of the University of Insubria, Varese. Director
of the Center for Thoracic Surgery, University of Insubria, Ospedale
di Circolo di Varese, Italy.
Appointed coordinator of Doctorate in Surgery and Biotechnologies.
|1) Strauss GM, Dominioni
L. Aftermath of the 1998 Varese Conference: a new scenario for lung
cancer screening. Proceedings of the International Conference pp 1-13
2) Dominioni L, Imperatori A, Rovera F, Paolucci M, Paddeu A. The
fairy-tale of overdiagnosis of lung cancer. Proceedings of the International
Conference pp 20-34 November 2003.
3) Imperatori A, Paddeu A, Rovera F, Bascialla L, Dominioni L. Epidemiology
of pleural mesothelioma in the Province of Como in the years 1996-2000.
Proceedings of the International Conference pp 41-48 November 2003.
4) Dominioni L, Paddeu A, Strauss GM. Proceedings of the International
Conference. Lung Cancer Screening and Early Diagnosis. Como, November
5) Dominioni L, Paddeu A, Strauss GM. Proceedings of the International
Conference. Pleural Mesothelioma. Como, November 2003.
6) Dominioni L, Rovera F, Imperatori A, Bascialla L, Pericelli A.
Chemioprofilassi antimicrobica nei pazienti chirurgici ad alto rischio.
XXII Congresso della Società Italiana di Chemioterapia, Milano
30 Novembre–3 Dicembre 2003.
7) Giaroni C, Zanetti E, Chiaravalli AM, Albarello L, Dominioni L,
Capella C, Lecchini S, Frigo G. Evidence for a glutamatergic modulation
of the cholinergic function in the human enteric nervous system via
NMDA receptors. Eur J Pharmacol 2003;476:63-69.
8) Rovera F, Billo P, Capella C, Dominioni L. Concurrent epithelial
thymoma and T-cell lymphoblastic lymphoma. European Journal of Cardio-thoracic
Surgery / Interactive Cardiovascular and Thoracic Surgery 2003;2:537-540.
9) Dominioni L, Rovera F, Pericelli A, Imperatori A. The rationale
of early enteral nutrition. Acta Bio Medica 2003;74:41-44.
10) Rovera F, Militello P, Antonini C, Imperatori A, Dominioni L.
Le polmoniti da Candida in 500 interventi di resezione polmonare.
Minerva Chirurgica 2004;59:45-51.
11) Cesario A, Trombino S, Galetta D, Margaritora S, Murolo C, Dominioni
L, Imperatori A, Festi L, Granone P, Russo P. Non-small cell lung
cancer: from cytotoxic systemic chemotherapy to molecular targeted
therapy. Curr Med Chem – Anti-Cancer Agents 2004;4:231-245.
12) Solomkin JS, Bjornson HS, Cainzos M, Dellinger EP, Dominioni L,
Eidus R, Faist E, Leaper D, Lee JT, Lipsett PA, Napoletano L, Nelson
CL, Sawyer RG, Weigelt J, Wilson SE. A consensus statement on empiric
therapy for suspected gram-positive infections in surgical patients.
Am J Surg 2004;187:134-145.
13) Dominioni L, Harrison R, Imperatori A, Leitch N, Sutton P, Rovera
F, Paolucci M. The outcome of asymptomatic lung cancer detected in
the year 2000 in Teesside District (UK) and in Varese District (Italy).
Proceedings of the 10th International Conference on Screening for
Lung Cancer, New York, 23-25 April 2004.
14) Dominioni L, Imperatori A, Pericelli A, Antonini C, Rotolo N,
Paolucci M. Videothoracoscopic (VTS) finger palpation and resection
of indeterminate lung nodules ≤ 1.5 cm. Evaluation of histology
by size groups. Proceedings of the 11th International Conference on
Screening for Lung Cancer, Roma, Italy 15-17 October 2004.
15) Cesario A, Russo P, Viaggi S, Trombino S, Imperatori A, Margaritora
S, Dominioni L, Festi L, Porziella V, Granone P. Malignant pleural
mesothelioma: time for translational research. The Lancet Oncology
16) Dominioni L, Imperatori A, Rovera F, Vassallo F, Rotolo N. Possibilità
di screening del carcinoma broncogeno. Risultati dello screening radiografico
in provincia di Varese negli anni 1997-2004. Atti della Società
Italiana di Chirurgia 2004; vol 2. Roma 17-20 ottobre 2004.
17) Pericelli A, Imperatori A, Vassallo F, Rotolo N, Dominioni L.
Resection of small indeterminate lung nodules by video-assisted thoracoscopic
surgery (VTS). Implications for the early diagnosis of lung cancer.
Rays 2004; 29(4):387-90.
18) Vassallo F, Imperatori A, Rovera F, Pericelli A, Antonini C, Dominioni
L. The PRE.DI.CA. project for radiographic lung cancer screening in
sigarette smokers. Rays 2004; 29(4):383-85.
19) Trombino S, Neri M, Puntoni R, Angelini C, Loprevite M, Cesario
A, Granone P, Imperatori A, Dominioni L, Ardizzoni A, Filiberti R,
Russo P. K-Ras Codon 12 mutation detected in plasma DNA is nota n
indicator of disease in NSCLC patients. Proceedings of the AACR Spacial
Conference in Cancer Research, San Diego, February 23-27, 2005
20) Cesario A, Catassi A, Festi L, Imperatori A, Pericelli A, Galetta
D, Margaritora S, Porziella V, Granone P, Dominioni L, Russo P. Farnesyltransferase
inhibitors and human malignant pleural mesothelioma: a first step
comparative traslational study. Clin Cancer Res 2005;11:2026-2037.
21) Strauss GM, Dominioni L, Jett JR, Freedman M, Grannis FW. Como
International Conference position statement. Lung cancer screening
for early diagnosis - five years after the 1998 Varese Conference.
Chest 2005; 127(4):1146-51.
22) Trombino S, Neri M, Puntoni R, Angelini C, Loprevite M, Cesario
A, Granone P, Imperatori A, Dominioni L, Ardizzoni A, Filiberti R,
Russo P. Mutations in K-ras codon 12 detected in plasma DNA are not
an indicator of disease in patients with non-small cell lung cancer.
Clin Chem. 2005;51(7):1313-4.
23) Imperatori A, Rotolo N, Pericelli A, Antonini C, Paolucci M, Dominioni
L. Videothoracoscopic (VTS) finger palpation and resection of indeterminate
lung nodules <1.5 cm. Evaluation of histology by size groups.The
24) Russo PA, Catassi A, Cesario A, Imperatori A, Rotolo N, Fini M,
Granone P, Dominioni L. Molecular Mechanisms of Hexavalent Chromium-induced
Apoptosis in Human Bronchoalveolar Cells. Am J Respir Cell Mol Biol.
2005 Sep 15; in press.
25) Imperatori A, Harrison RN, Leitch DN, Lepore G, Rovera F, Dionigi
G, Sutton P, Dominioni L. Lung cancer in Teesside (UK) and in Varese
(Italy): a comparison of management and survival. Thorax 2005.
26) Cesario A, Granone P, Dominioni L, Russo P. Remarks on adjuvant
chemoterapy with Tegafur-Uracil in Non-small-Cell Lung Cancer. Chest
2005 – Letters to the Editor; 128 (4): 2933-43.
epidemiology, screening, bronchoscopy, treatment
identification of high-risk patient; high-dose immunoglobulins treatment
in severely septic patients
parenteral and enteral nutrition of surgical and severely septic patients
advances in video-assisted thoracoscopic surgery; treatment of small
Malignant pleural mesothelioma
Surgical treatment and multimodal therapy