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The University of Insubria CV
The University of Insubria CV
The University of Insubria CV The University of Insubria CV Andrea Penoni
The University of Insubria CV
 

Contact data

Assistant Professor
Department of Chemical and Environmental Sciences
via Valleggio 11, I-22100
Tel: +39-031-2386440
Fax: +39-031-2386449
E-mail: andrea.penoni@uninsubria.it

 

Biography

Penoni Andrea studied Chemistry at the Università Statale in Milan and graduated (Laurea degree) in 1996 under the supervision of Prof. Sergio Cenini with a thesis on "Amination reactions of olefins catalyzed by transition metal complexes".

He got a Ph.D. position in 1996 in Cenini's group and worked on a project on organometallic chemistry and homogeneous catalysis. In 2000 after the doctoral degree with a disertation on "Catalytic amination reactions of unsaturated hydrocarbons", he completed postdoctoral studies in Milan on "Transition metal carbene and nitrene complexes as intermediate in in the organic synthesis" (supervisior Prof. S. Cenini).

In 2000-01 he joined Kenneth M. Nicholas at the University of Oklahoma in Norman, Oklahoma where he studied a novel catalytic reductive annulation of nitro- and nitrosoaromatics with alkynes.
He returned to Milan at the end of 2001 and since 2003 he is an Assistant Professor in Organic Chemistry at the Università dell'Insubria in Como where he joined the Prof. Giovanni Palmisano's research group. At the end of 2003 he spent three months in Nicholas' group at the University of Oklahoma studying synthesis of azaindoles and N-methoxyindoles. His research is particularly directed to the synthesis of nitrogen containing heterocycles and new C-N bond formation mediated by metals and/or metal complexes.
 

Qualifications and awards

Member of the Italian Chemical Society
 

Research interests

New strategies for the synthesis of heterocyclic molecules with indole and pyrrole skeletal

Use of transition metal-complexes for the formation of new C-C and C-N bonds for the cyclopropanation, aziridination and amination processes.

Study of the reactivity and functionalization of organic molecules by the use of reactions in homogeneous and heterogeneous catalysis.
National and International collaborations:

Prof G. Cravotto (Università degli Studi di Torino)
Prof. G. B. Giovenzana (Università degli Studi del Piemonte Orientale)
Prof A. Maldotti (Università degli Studi di Ferrara)
Prof. K. M. Nicholas (University of Oklahoma, USA)
 

Teaching experience and appointments

Laboratory of Organic Chemistry
Laboratory of Organic Synthesis
Environmental Organic Chemistry
 

Representative  publications

1. S. Cenini, A. Penoni, S. Tollari.
“Tetraalkylammonium N-Chloro-p-toluensulfonamide as Aminating Agent of Olefins.”
J. Mol. Catal. : A Chemical. 1997, 124, 109.

2. S. Cenini, S. Tollari, A. Penoni, C. Cereda.
“Catalytic Amination of Unsaturated Hydrocarbons: Reactions of p-Nitrophenylazide with Alkenes Catalysed by Metallo-porphyrins.”
J. Mol. Catal. : A Chemical. 1999, 137, 135.

3. S. Tollari, A. Penoni, S. Cenini.
“The Unprecedented Detection of the Intermediate of N-Hydroxy derivatives during the Carbonylation of 2'-Nitrochalcones and 2-Nitrostyrenes Catalysed by Palladium.”
J. Mol. Catal. : A Chemical 2000, 152, 47.

4. A. Maldotti, L. Andreotti, A. Molinari, S. Tollari, A. Penoni, S. Cenini.
“Photochemical and photocatalytic reduction of nitrobenzene in the presence of cyclohexene.”
J. Photochem. Photobiol. A: Chem. 2000, 133, 129.

5. S. Cenini, G. Cravotto, G. B. Giovenzana, A. Penoni, S. Tollari, G. Palmisano
"Rhodium (II) catalysed decomposition of 3-diazo-4-hydroxycoumarin. An easy access to furocoumarin ring system."
J. Mol. Catal. : A Chemical 2000, 164, 165.

6. S. Tollari, S. Cenini, A. Penoni, G. Granata, G. Palmisano, F. Demartin " Carbene complexes of cycloplatinated 1-H-Indole-1-Methyil-2-(2'-pyridine). The crystal and molecular structure of s - í Pt[ 1H-indole-1-methyl-2-(2'-pyridinil-C3, N'](DMSO) Cl ý and of s - í Pt[1H-indole-1-methyl-2-(2'-pyridinil-C3,N'][=C(OCH2CH3)(CH2C6H5)] Cl ý " J. Organomet . Chem. 2000 , 608 , 34.

7. S. Cenini, E. Gallo, A. Penoni
"Carbon-Nitrogen bond formation catalysed by Metallo-Porphyrins."
Chim.Ind. (Milan) 2000, 82, E1/1-E1/8.

8. S. Cenini, E. Gallo, A. Penoni, F. Ragaini, S. Tollari
"Amination of benzylic C-H bonds by arylazides catalysed by CoII(porphyrin) complexes. A new reaction leading to secondary amines imines."
Chem. Commun. 2000, 2265.

9. S. Tollari, G. Palmisano, S. Cenini, G. Cravotto, G. B. Giovenzana, A. Penoni,
"Synthesis of furocoumarins via rhodium (II)-catalysed heterocyclisation of 3-diazo-benzopyran-2,4(3H)-dione with terminal alkynes."
Synthesis 2001, 735.

10. E. Gallo, F. Ragaini, A. Penoni, E. Mangioni, S. Cenini
"The Metallo-Porphyrins: an efficient model of natural enzymes. Mechanistic studies of the catalytic amination of benzylic groups." IT
Rendiconti – Istituto Lombardo Accademia di Scienze e Lettere B: Scienze Chimiche e Fisiche, Geologiche, Biologiche e Mediche 2001, 135, 241.

11. A. Penoni, K. M. Nicholas
"Regioselective Synthesis of Indoles via Catalytic Reductive Annulation of Nitroaromatics with Alkynes."
Chem. Commun. 2002, 484.

12. A. Penoni, J. Volkmann, K. M. Nicholas
"Regioselective Synthesis of Indoles via Catalytic Reductive Annulation of Nitrosoaromatics with Alkynes"
Org. Lett. 2002, 4, 699.

13. S. Cenini, G. Cravotto, G. B. Giovenzana, G. Palmisano, A. Penoni, S. Tollari
"Diruthenium (II;II) tetrakis(acetate) as a catalyst of choice for intermolecular insertion of stabilized diazocompounds into O-H bonds"
Tetrahedron Lett. 2002, 43, 3637.

14. F. Ragaini, A. Penoni, E. Gallo, S. Tollari, C. Li Gotti, M. Lapadula, E. Mangioni, S. Cenini
"Amination of benzylic C-H bonds by arylazides catalysed by CoII(porphyrin) complexes. A synthetic and mechanistic study."
Chem. Eur. J., 2003, 9, 249.

15 A. Penoni, R. Wanke, S. Tollari, E. Gallo, D. Musella, F. Ragaini, F. Demartin, S. Cenini
"Cyclopropanation of olefins with diazoalkanes, catalyzed by CoII(porphyrin) complexes. A synthetic and mechanistic investigation and the molecular structure of CoIII(TPP)(CH2CO2Et) (TPP=dianion of meso-tetraphenylporphyrin)."
Eur. J. Inorg. Chem., 2003, 1452.

16. A. Maspero, S. Brenna, S. Galli, A. Penoni
" Synthesis and Characterization of New Polynuclear Copper(I) Pyrazolate Complexes and Their Catalytic Activity in the Cyclopropanation of Olefins”.
J. Organomet. Chem. 2003, 672, 123.


17. G. Cravotto, A. Demetri, G. M. Nano, G. Palmisano, A. Penoni, S. Tagliapietra
"The Aldol Reaction under High-Intensity Ultrasound: A Novel Approach to an Old Reaction"
Eur. J. Org. Chem. , 2003, 4438.

18. E. M. Beccalli, G. Broggini, G. Paladino, A. Penoni, C. Zoni
"Regioselective Formation of Six- and Seven-membered Ring by Intramolecular Pd-Catalyzed Amination of N-Allyl-anthranilamides"
J. Org. Chem. , 2004, 69, 5627.

19. G. Broggini, I. De Marchi, M. Martinelli, G. Paladino, A. Penoni
"Intramolecular Azide Cycloaddition en route to the New Pyrrolo[2,1-c][1,2,3]triazolo[1,5-a][1,4]benzodiazepine Skeleton"
Letters Org. Chem. , 2004, 1, 221.

20. G. Cravotto, G. Balliano, S. Tagliapietra, G. Palmisano, A. Penoni
"Umbelliferone aminoalkyl derivatives, a new class of squalene-hopene cyclase inhibitors"
Eur. J. Med. Chem. , 2004, 39, 917.

21. G. Cravotto, G. Palmisano, S. Tollari, G. M. Nano, A. Penoni
"The Suzuki homocoupling reaction under high-intensity ultrasound"
Ultrason. Sonochem. , 2005, 12, 91.

22. G. Cravotto, M. Beggiato, A. Penoni, G. Palmisano, J. M. Leveque, W. Bonrath
”High-intensity Ultrasound and Microwave, Alone or Combined, promote Pd/C-catalyzed aryl-aryl couplings”
Tetrahedron Lett., 2005, 46, 2267.

23. A. Maldotti, R. Amadelli, L. Samiolo, A. Molinari, A. Penoni, S. Tollari, S. Cenini
”Photocatalytic formation of a Carbamate through Ethanol-Assisted Carbonylation of p-Nitrotoluene”
Chem. Commun., 2005, 1749.

24. G. B. Giovenzana, G. Palmisano, E. Del Grosso, L. Giovannelli, A. Penoni, T. Pilati
”Polycyclic Compounds from Aminopolyols and Alpha-dicarbonyls: Structure and Application in the Synthesis of Exoditopic Ligands”
Org. Biomol. Chem., 2005, 1489.

25. L. Goldoni, G. Cravotto, A. Penoni, S. Tollari, G. Palmisano
”The Rhodium Carbenoid Route to 3-Aryl-4-hydroxycoumarins: Synthesis of Derrusnin”
Synlett, 2005, 927.

26. G. Cravotto, F. Demartin, G. Palmisano, A. Penoni, T. Radice, S. Tollari
”Novel Cyclometallated Pd(II) and Pt(II) Complexes with Indole Derivatives and Their Use as Catalysts in Heck Reaction”
J. Organomet. Chem., 2005, 690, 2017.

 

 

 
   
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